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Synthetic Organic Chemistry - EPSRC Reserach Area

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Recent EPSRC Grants for Synthetic Organic Chemistry

Title Principal Investigator Organization Start Date End Date Value
Novel ionic-based tools for glycoscience Galan, M (Dr) University of Bristol 31/03/2012 30/03/2017 £920,060
New Chemistry Approaches for the Next Generation of Healthcare Marquez, R (Dr) University of Glasgow 31/03/2010 30/03/2015 £1,032,742
Cascade Catalysis: From Alkynes to Polycycles Anderson, EA (Dr) University of Oxford 31/01/2013 30/01/2015 £235,426
Preparation of Heterogeneous Catalysts for Stereoselective Transformations Jones, MD (Dr) University of Bath 29/09/2008 28/09/2012 £216,839
A Unified Route to Bicyclic Heterocycles: Synthesis and Applications Anderson, EA (Dr) University of Oxford 28/06/2010 27/07/2013 £319,766
Mass Spectrometry to Support Synthetic Chemistry in Durham Steel, P (Dr) Durham University 27/03/2009 26/03/2013 £420,938
Giants of the Infinitesimal Raval, R (Professor) University of Liverpool 24/08/2009 31/01/2013 £134,984
Group 2: Elements of 21st Century Catalysis Hill, MS (Professor) University of Bath 23/05/2011 22/11/2014 £427,178
Boronic Acids for Dye Sensitised Solar Cells Fossey, JS (Dr) University of Birmingham 23/04/2012 22/04/2014 £87,254
Quantifying the Interplay of Structure and Reactivity in Ring Closing and Cross Metathesis Percy, JM (Professor) University of Strathclyde 21/07/2009 20/07/2012 £256,115
Oxidative processes - from amino acids to heterocycles, complexity from simplicity Moody, CJ (Professor) University of Nottingham 21/05/2012 04/07/2015 £341,242
The CF2 group as a conformational tool in the olfactory receptor response O'Hagan, D (Professor) University of St Andrews 20/05/2013 19/05/2016 £328,399
Collaborative research visit to the California Institute of Technology Conway, SJ (Dr) University of Oxford 20/03/2013 19/09/2013 £18,180
Theoretical and Experimental Studies of Metal Catalysed Reactions and Boron-Containing Optical Materials Marder, T (Professor) University of Wuerzburg 19/10/2009 18/07/2012 £52,613
Synthesis of glycosyl-novobiocins: probes of Hsp90 C-terminal affinity binding and novel anti-cancer drugs Simon, B (Dr) University College London 19/08/2013 18/08/2015 £99,144
CO2Chem Grand Challenge Network Styring, P (Professor) University of Sheffield 18/06/2012 17/06/2017 £445,777
International Collaboration in Chemistry: Structural Mechanostereochemistry of Mechanically Interlocked Polymers and Networks Slawin, AMZ (Professor) University of St Andrews 18/01/2010 17/01/2013 £492,427
Synthetic probes of histidine phosphorylation: new reagents for systems biology and proteomics Webb, ME (Dr) University of Leeds 17/01/2011 16/01/2013 £100,937
Realising lead-oriented synthesis Nelson, AS (Professor) University of Leeds 16/04/2012 15/04/2015 £533,045
Porphyrin Nanorings Malfois, M (Dr) Diamond Light Source 16/01/2012 15/01/2015 £12,609
Convergent Acyliminium Methodology: Diversity in Heterocyclic Scaffolds Taylor, R (Professor) University of York 15/10/2012 14/10/2015 £318,479
Harnessing Sulfur Dioxide for Catalysis Willis, M (Professor) University of Oxford 15/04/2013 14/04/2016 £355,390
Changing the Synthesis Landscape with Boron at the Helm: from Chiral Organometallics to Assembly Line Synthesis Aggarwal, VK (Professor) University of Bristol 14/05/2012 13/05/2017 £1,578,875
Artificial Photosynthesis: Solar Fuels Cogdell, RJ (Professor) University of Glasgow 12/01/2009 11/04/2013 £1,559,914
Gold-Catalysed Direct Allylic Etherification of Alcohols Lee, A (Dr) Heriot-Watt University 11/03/2013 10/03/2016 £570,861
Complexity-Generating Hydration Reactions via Metal-Catalysed Reaction of Boronic Acids with Alkenes Sheppard, TD (Dr) University College London 10/09/2012 09/09/2015 £345,136
Thiyl Radicals and Isocyanides: A New Approach Towards Biologically Active Heterocycles Hilton, S (Dr) University College London 10/09/2012 09/09/2014 £100,205
Dream Fellowship. Innovations in Catalysis Williams, JMJ (Professor) University of Bath 10/08/2011 10/05/2013 £119,935
Magnetic Resonance of Dihydrogen Endofullerenes Horsewill, AJ (Professor) University of Nottingham 10/02/2012 09/02/2015 £26,182
Cross-Metathesis Based Routes to Heteroaromatic Systems Donohoe, T (Professor) University of Oxford 10/01/2011 09/01/2013 £218,279
Highly Convergent Total Synthesis of Gambieric Acid A Using Iterative and Two-Directional Ring-Closing Metathesis Reactions Clark, JS (Professor) University of Glasgow 09/09/2008 08/09/2012 £934,147
Asymmetric Cross-Coupling via Iron-Catalysed Reductive Cross-Coupling Thomas, SP (Dr) University of Bristol 09/01/2012 08/01/2013 £99,842
Investigating the influence of fluorination on hydrogen bonding properties of functional groups Linclau, B (Dr) University of Southampton 08/04/2013 07/04/2015 £227,273
Probing the extraordinary bioactivity of macrocyclic natural products: privileged motifs or biosynthetic artefacts? Nelson, AS (Professor) University of Leeds 07/11/2008 10/12/2012 £420,891
A Claisen-Sakurai Strategy to Highly Substituted Cyclopentenols: Applications to the Syntheses of Echinopine A and B Cook, MJ (Dr) Queen's University of Belfast 07/09/2010 06/09/2012 £100,847
Dial-a-Molecule Grand Challenge Network continuation Whitby, RJ (Professor) University of Southampton 07/05/2012 06/05/2015 £450,269
An Extraordinary Photochemical Reaction of Pyrrole - A New Tool for Molecular Complexity Booker-Milburn, KI (Professor) University of Bristol 07/01/2013 06/01/2016 £308,399
Selective activation of chemical bonds by active coherent THz spectrometry Donnan, RS (Dr) Queen Mary, University of London 06/12/2010 05/07/2012 £246,814
Organometallic Synthesis of Reactive Nanoparticles for Radically New Solder Materials Mannan, S (Professor) King's College London 06/07/2009 31/12/2012 £649,673
New Multiple Bond-Forming Strategies for Organic Synthesis France, D J (Dr) University of Glasgow 06/06/2011 05/06/2013 £102,084
Methodology for, and Synthesis of Biologically Active Pyrrolidinone Natural Products. Burton, JW (Dr) University of Oxford 05/11/2012 04/11/2015 £360,823
Rhodium-Catalysed Ynamide Carbometallations for Stereoselective Synthesis Lam, HW (Dr) University of Edinburgh 05/10/2009 04/10/2012 £301,253
Preparation and Applications of New Highly Active P-Chiral Phosphine Oxide Catalysts Jones, S (Dr) University of Sheffield 04/02/2013 03/02/2016 £318,625
Synthesis of ingenol using a new method of inside-outside stereocontrol Grainger, RS (Dr) University of Birmingham 04/01/2010 03/01/2013 £286,596
Direct Alkene and Alkyne Borylation with Borenium Cations Ingleson, MJ (Dr) The University of Manchester 03/01/2012 02/07/2015 £362,403
Chemistry Cascades: Synthesis of prostratin analogues for evaluation against HIV Procter, DJ (Professor) The University of Manchester 01/12/2010 30/11/2013 £297,875
Cu(II)-Catalysed C-H Activation Routes to Heterocycles; Applications in Target Synthesis Taylor, R (Professor) University of York 01/11/2012 31/10/2015 £313,432
Extending fluorinase [C-18F]-bond biocatalysis for Positron Emission Tomography (PET) O'Hagan, D (Professor) University of St Andrews 01/11/2011 31/10/2014 £319,972
New Transition Metal Catalysed Methods for Alkyl C-N Bond Formation Bower, J (Dr) University of Bristol 01/11/2011 31/10/2013 £86,084
Extending the range of tamponades for the delivery of therapeutic agents to treat proliferative vitreoretinopathy Kearns, VR (Dr) University of Liverpool 01/10/2013 30/09/2014 £98,686
Cyclizations and cyclization cascades triggered by new reductions Procter, DJ (Professor) The University of Manchester 01/10/2013 30/09/2016 £291,075
Enantioselective Amine alpha-C-H Functionalisation via Copper/Chiral Anion Cooperative Catalysis Watson, A J B (Dr) University of Strathclyde 01/10/2012 30/09/2013 £96,898
Regiospecific, Controlled Synthesis of Structurally Defined Peptide Scaffolds Cobb, SL (Dr) Durham University 01/10/2012 30/09/2013 £99,889
Group 2: Elements of 21st Century Catalysis Barrett, T (Professor) Imperial College London 01/10/2011 31/03/2015 £336,415
Magnetic Resonance of Dihydrogen Endofullerenes Levitt, MH (Professor) University of Southampton 01/10/2011 30/09/2014 £512,959
Extending fluorinase [C-18F]-bond biocatalysis for Positron Emission Tomography (PET) Zanda, M (Professor) University of Aberdeen 01/10/2011 30/09/2014 £56,055
Development of a General sp2-sp3 Coupling Methodology Stockman, RA (Dr) University of Nottingham 01/10/2011 30/09/2015 £141,893
Metal Catalysed Decarboxylative C-C Bond Formation Reactions Larrosa, I (Dr) Queen Mary, University of London 01/10/2011 31/03/2015 £321,006
Novel strategies to access chiral heterocycles as potential lead compounds in drug discovery Bull, JA (Dr) Imperial College London 01/10/2011 30/09/2016 £723,115
Chiral Concepts in s-Block Metal Amide Chemistry O'Hara, C (Dr) University of Strathclyde 01/10/2011 30/09/2016 £907,993
Increasing the Efficiency of Chemical Synthesis Using Asymmetric Transition Metal Catalysis Lam, HW (Dr) University of Edinburgh 01/10/2010 30/09/2015 £970,525
Changing the nature of chemical synthesis through metal catalyzed C-H bond functionalization Gaunt, M (Professor) University of Cambridge 01/10/2010 30/09/2015 £2,016,328
Synthesis of complex aminoacids and the microsclerodermins Donohoe, T (Professor) University of Oxford 01/10/2010 30/09/2012 £246,036
Mechanistic Studies of Nucleophilic Organocatalysis by N-Heterocyclic Carbenes O'Donoghue, AC (Dr) Durham University 01/10/2009 31/03/2013 £277,311
Reagent-Free Flow Chemistry: The Generation and Trapping of Reactive Intermediates Whitby, RJ (Professor) University of Southampton 01/10/2009 30/09/2013 £392,524
A Holistic Doctoral Training Centre for Chemical Synthesis Booker-Milburn, KI (Professor) University of Bristol 01/10/2009 31/03/2018 £8,086,497
Doctoral Training Centre in Sustainable Chemical Technologies Davidson, MG (Professor) University of Bath 01/10/2009 31/03/2018 £7,492,223
Photopatterned Dendrons for Tissue Engineering Applications De Bank, PA (Dr) University of Bath 01/10/2009 30/09/2012 £302,850
Heterointerface control of organic semiconductor devices Friend, R (Professor Sir) University of Cambridge 01/10/2009 31/12/2014 £6,693,636
Adsorbate-induced chiral reconstructions studied by surface X-ray diffraction Held, G (Professor) University of Reading 01/10/2009 30/09/2013 £177,322
Synthesis and Characterisation of Dual Functional Nanoparticles for Probing the Role of Reactive Oxygen Species in Cellular Function Aylott, J (Dr) University of Nottingham 01/10/2009 31/03/2013 £103,454
Synthesis and Characterisation of Dual Functional Nanoparticles for Probing the Role of Reactive Oxygen Species in Cellular Function Beeby, A (Professor) Durham University 01/10/2009 31/12/2012 £131,241
Alkenes as Nucleophiles in Catalytic Asymmetric C-C Bond Formation Fletcher, S P (Dr) University of Oxford 01/10/2009 30/09/2014 £963,937
The Carbon Factory: A laboratory for the chemistry of carbon-rich systems Low, P (Professor) Durham University 01/10/2009 30/09/2014 £1,354,343
Under water control: A cascade approach to the pseudolaric acid anti-tumour agents Procter, DJ (Professor) The University of Manchester 01/10/2009 30/09/2013 £146,280
Highly anisotropic helicene-based NLOphores for Two Photon Circular Dichroism (TPCD) Stephenson, GR (Dr) University of East Anglia 01/10/2009 30/09/2013 £268,079
Rapid synthesis of complex bioactive alkaloids Simpkins, NS (Professor) University of Birmingham 01/10/2009 30/09/2012 £302,161
Chemical Analysis of Hybrid Fungal Megasynthases Cox, R (Professor) University of Bristol 01/10/2008 30/09/2012 £700,411
New array strategies using C-H borylation chemistry Steel, P (Dr) Durham University 01/10/2008 31/12/2012 £504,222
A Synthesis Programme at Cambridge Ley, S (Professor) University of Cambridge 01/10/2008 30/03/2014 £3,418,103
New Synthesis-Enabling Reactions and Reaction Cascades for the Discovery and Production of Potential Anti-Cancer Compounds Dixon, DJ (Professor) University of Oxford 01/10/2008 31/03/2014 £1,336,583
General and Convergent Strategy for Asymmetric Synthesis Aggarwal, VK (Professor) University of Bristol 01/10/2007 31/03/2013 £984,771
High Energy Metal-Based Compounds: The Road to Perazametallocene Portius, P (Dr) University of Sheffield 01/10/2007 30/09/2012 £695,450
From Total Synthesis-Inspired Methodology to Anti-HIV therapy Anderson, EA (Dr) University of Oxford 01/10/2007 30/09/2012 £666,639
Restricted Diversity; Constrained Diversity-Oriented Synthesis Spring, D (Dr) University of Cambridge 01/09/2012 31/08/2017 £1,541,796
Efficient Catalytic and Asymmetric and Cycloaddition Routes to Future Medicines Dowden, J (Dr) University of Nottingham 01/09/2012 31/08/2015 £339,660
Alignment of Synthesis, Medicinal Chemistry and Structural Genomics to Accelerate UK Drug Discovery: Network SMS-Drug Tomkinson, NCO (Professor) University of Strathclyde 01/09/2011 31/08/2015 £184,149
COLLABORATIVE RESEARCH IN ENERGY WITH SOUTH AFRICA: UPGRADING OF LIGHT ALKANES TO FUELS Hutchings, GJ (Professor) Cardiff University 01/09/2010 31/08/2013 £384,905
Enantioselective New Metal-Catalysed Carbocyclisation Reactions Aissa, C (Dr) University of Liverpool 01/09/2009 30/11/2014 £516,724
Rearrangement of cis-fused beta-lactams into the 6-azabicyclo[3.2.1]octane ring system Grainger, RS (Dr) University of Birmingham 01/09/2009 28/02/2013 £144,003
Metal-Bronsted Acid Cooperative Catalysis for Asymmetric Direct Reductive Amination Xiao, J (Professor) University of Liverpool 01/09/2009 30/06/2013 £453,880
Hydrogenation of ketones without transition metal catalysts. Wills, M (Professor) University of Warwick 01/09/2009 28/02/2013 £134,230
Synthetic Nanomachines Driven Through Metal-Ligand Exchange Reactions Lusby, PJ (Dr) University of Edinburgh 01/09/2009 31/08/2013 £212,515
Organic Catalysts Incorporating Catalytic Triads Sheppard, TD (Dr) University College London 01/09/2007 31/08/2012 £567,456
Total synthesis of the cylindrospermopsin alkaloids Murphy, P (Dr) Bangor University 01/08/2012 31/07/2014 £184,635
Sustainable Phosphorus Chemistry: Catalytic Asymmetric SN2 Reactions Denton, RM (Dr) University of Nottingham 01/08/2011 31/07/2014 £344,114
Catalytic Dehydrocoupling of Amine-Borane Adducts: A Route to Polyaminoboranes, Boron-Nitrogen Analogues of Polyolefins Manners, I (Professor) University of Bristol 01/08/2010 31/01/2014 £311,852
Multivicinal fluorinated cyclohexanes, a new structural motif in organic chemistry O'Hagan, D (Professor) University of St Andrews 01/08/2010 31/07/2013 £317,651
The E-Word and other Chemical Stories Sella, A (Dr) University College London 01/08/2010 31/07/2012 £114,442
Nanoengineered Materials for Clean Catalytic Technologies Lee, AF (Professor) University of Warwick 01/08/2009 30/09/2014 £1,532,389
Giants of the Infinitesimal Moriarty, P (Professor) University of Nottingham 01/08/2009 31/07/2012 £12,138
Bioactive Natural Product Assembly Using Precious Metal Catalysis: Total Synthesis of Phyllostictine A Shipman, M (Professor) University of Warwick 01/07/2013 30/06/2016 £415,371
Light-Activated Approaches to Highly Challenging Organic Electron Transfer Reactions Murphy, JA (Professor) University of Strathclyde 01/07/2013 30/06/2015 £211,857
New Catalytic C-H Functionalisations and Oxidative Annulations for Chemical Synthesis Lam, HW (Dr) University of Edinburgh 01/07/2013 30/06/2015 £175,939
Catalytic Stereoselective Synthesis of Glycosides Galan, M (Dr) University of Bristol 01/07/2013 30/06/2015 £241,631
Innovative targets for circadian drug discovery: REV-ERBalpha and RORalpha Tomkinson, NCO (Professor) University of Strathclyde 01/07/2011 31/12/2014 £1,210,241
A Photochemical Approach to Dimeric Diazoparaquinones Inspired Through Biosynthetic Speculation Moses, JE (Dr) University of Nottingham 01/07/2011 30/06/2014 £341,505
3D Libraries Consortium Wyatt, PG (Professor) University of Dundee 01/07/2011 31/12/2013 £198,855
Convergent syntheses of bryostatins Thomas, EJ (Professor) The University of Manchester 01/07/2010 31/12/2012 £209,019
Development of novel catalytic structures and thermal regimes for continuous flow reaction chemistry Haswell, S (Professor) University of Hull 01/07/2009 31/12/2012 £328,251
New Generic Synthetic Protocols for Pharmaceutical Intermediates Based on Continuous Flow Multifunctional Platforms Williams, JMJ (Professor) University of Bath 01/07/2009 16/05/2013 £568,296
Powerful new methods for the synthesis of peptides: catalytic oxidation reactions tested to the limit Donohoe, T (Professor) University of Oxford 01/06/2013 31/05/2015 £225,051
Microporous materials based on Organic Molecules of Intrinsic Microporosity McKeown, N (Professor) Cardiff University 01/06/2010 31/05/2013 £324,136
Challenging Ozonolysis Gavriilidis, A (Professor) University College London 01/06/2009 31/08/2012 £469,908
Investigating the Potential Of Polymer-Scaffolded Dynamic Combinatorial Libraries Fulton, DA (Dr) Newcastle University 01/06/2009 31/03/2014 £318,328
New Catalytic C-H Activation and Decarboxylation Chemistry for Synthesis Greaney, M (Professor) The University of Manchester 01/05/2013 30/04/2015 £341,429
Functionalised Silicon Double Bonds Scheschkewitz, D (Dr) Imperial College London 01/05/2011 31/03/2014 £206,968
New molecular tools for the 21st century: Molecular design of new DNA-based devices Burley, GA (Dr) University of Strathclyde 01/04/2011 31/03/2013 £230,121
Triple Diels-Alder Cascades: Development and Application to Daphnezomine Synthesis Taylor, R (Professor) University of York 01/04/2010 31/03/2013 £297,057
An Investigation of Multicomponent Azole Chemistry within a Generational System for the Expression the Canonical Genetic Structures Powner, M W (Dr) University College London 01/03/2013 28/02/2018 £970,490
EPSRC-Royal Society fellowship engagement (2012) The Union of Asymmetric Organocatalysis with Transition Metal Chemistry Cordier, C J (Dr) Imperial College London 01/03/2013 29/02/2016 £315,313
Synthesis of Amides from Nitriles via Multifaceted Catalysis Camp, J E (Dr) University of Nottingham 01/03/2012 28/02/2013 £99,711
Porphyrin Nanorings Anderson, HL (Professor) University of Oxford 01/03/2012 28/02/2015 £578,131
New catalytic strategies for chemical synthesis: Catalytic Enantioselective Dearomatization Gaunt, M (Professor) University of Cambridge 01/03/2011 31/08/2014 £624,268
The Primary Phosphine Renaissance Higham, LJ (Dr) Newcastle University 01/03/2009 31/03/2014 £919,531
Metal-free Arylations for Green Chemistry Wirth, T (Professor) Cardiff University 01/02/2012 31/01/2015 £354,904
Molecular mechanisms of antimicrobial peptides: phase changes induced in endotoxic bacterial lipopolysaccharide. Harvey, RD (Dr) King's College London 01/02/2010 31/01/2014 £195,662
Synthesis and Characterisation of Dual Functional Nanoparticles for Probing the Role of Reactive Oxygen Species in Cellular Function Boyle, R (Professor) University of Hull 01/02/2010 30/04/2013 £251,403
Fully-Integrated Continuous Flow Processes for Access to Forbidden Chemistries, New Reactivities and Sequential Complexity Generation Ley, S (Professor) University of Cambridge 01/01/2013 31/12/2017 £2,559,199
New Porphycene Macrocycles for Applications in Two-Photon Absorption: Optimisation and Synthesis Paterson, MJ (Professor) Heriot-Watt University 01/01/2012 31/12/2014 £471,671
Porphyrin Nanorings Beton, PH (Professor) University of Nottingham 01/01/2012 31/12/2014 £226,563
Directed Covalent Assembly in the Solid State: towards Predictable Solvent-free Synthesis Sanders, J (Professor) University of Cambridge 01/01/2012 31/03/2016 £836,027
Design, synthesis and application of novel cytochrome P450 probes Sellars, JD (Dr) Durham University 01/01/2010 31/12/2012 £252,105
Development of An Asymmetric Radical Cyclisation and Application in the Synthesis of Nakadomarin A Stockman, RA (Dr) University of Nottingham 01/01/2010 30/09/2013 £285,439
Organic Dications: Synthesis, Reactivity and Applications Murphy, JA (Professor) University of Strathclyde 01/01/2010 30/06/2013 £423,998